This section focuses on an overview of disodium guanylate (GMP) as well as its manufacturing processes and uses. Also, please check out the introduction to disodium guanylate manufacturers, supply chain issues, disodium guanylate suppliers, and disodium guanylate prices. Sinofi can help you buy high-quality disodium guanylate powder in bulk for your industry applications at wholesale prices based on E627 and CAS 5550-12-9.
Table of Contents
What is Disodium Guanylate (GMP)?
Disodium guanylate (E627, disodium 5′-guanylate) is a widely used flavor enhancer in the food industry, known for intensifying savory or umami tastes. Disodium guanylate is the disodium salt of guanosine monophosphate, a naturally occurring nucleotide. It is a common flavor enhancer often used in combination with monosodium glutamate (MSG) and disodium inosinate in processed foods. I+G, a 1:1 mixture of IMP and GMP, is more widely used in the food industry due to its superior flavor-enhancing capabilities. According to the U.S. Food and Drug Administration (FDA), disodium guanylate is approved to be used in food flavouring.
Regulatory Status and Safety Considerations
Disodium guanylate has also been evaluated by major regulatory authorities like JECFA, EFSA, EUR-Lex, ECHACHEM, FEMA and WHO. It is widely permitted as a flavour enhancer. In the European Union it is authorised as E 627 under Regulation (EC) No 1333/2008, generally as part of the guanylic acid and guanylates group and frequently subject to combined group maximum levels with the related additives E 626 to E 629. In the United States it is listed under 21 CFR 172.530 as a food additive permitted for direct addition. JECFA has evaluated the 5′-ribonucleotides and established an acceptable daily intake of “not specified”, indicating that no numerical limit was considered necessary on the toxicological evidence available.
CAS No.: 5550-12-9
According to the American Chemical Society, the CAS number of disodium guanylate is 5550-12-9.
E number: E627
According to the European Food Safety Authority (EFSA), disodium guanylate is designated as food additive E627. It is a versatile flavor enhancer due to its unique properties.
Bulk Disodium Guanylate Manufacturers
The global disodium guanylate manufacturing landscape is dominated by Asian producers, with Japanese and Korean companies leading in terms of production capacity. Top disodium guanylate manufacturers include some companies in Japan, South Korea, and China. Large companies like Ajinomoto operate large-scale fermentation and processing facilities in many countries. They operate globally, supplying disodium guanylate to the food industry worldwide. These companies typically operate as primary manufacturers, converting raw materials into disodium guanylate through bio-fermentation processes.
Sinofi is a bulk disodium guanylate manufacturer in China, and we have a manufacturing facility with 2,500 square meters for the production of disodium guanylate. We supply high-quality disodium guanylate at bulk prices for our clients in the food industry.
Manufacturing Process of Disodium Guanylate
The manufacturing process of disodium guanylate involves several steps, from the synthesis of guanylic acid to the final crystallization and quality control. The production of disodium guanylate typically follows these steps:
- Produce guanosine through biofermentation.
- Nucleoside phosphorylase catalyzes guanosine to produce disodium 5′-guanylate by using guanosine and sodium pyrophosphate aqueous solution as substrates.
- Concentration and crystallization.
- Drying.
Bulk Disodium Guanylate Suppliers
Disodium guanylate suppliers play crucial roles in ensuring the availability of disodium guanylate across the global food industry. Top suppliers like Ajinomoto have an extensive network of international distributors. They supply to:
- Food ingredient distributors.
- Food manufacturing companies.
- Flavor houses and seasoning manufacturers.
- International trading companies that handle bulk ingredients.
Sinofi is a bulk disodium guanylate supplier in China, and we have a warehouse with 1,200 square meters for high-quality disodium guanylate E627. We supply different grades of disodium guanylate at wholesale prices to food manufacturers around the world.
Supply Chain of Disodium Guanylate
The global disodium guanylate supply chain is dominated by major Asian manufacturers, particularly from Japan, South Korea, and China It generally works as follows:
- Raw material sourcing (often from agricultural products).
- Manufacturing through fermentation or chemical synthesis.
- Quality control and certification.
- Distribution to industrial customers.
- Final use in food products.
Wholesale and Buy Disodium Guanylate in Bulk
Successful buying of disodium guanylate in wholesale requires careful attention to quality, regulatory compliance, and supplier relationships. By following proper procurement procedures and maintaining high standards, disodium guanylate buyers can ensure a reliable supply of this important food additive.
- Develop strong relationships with reliable disodium guanylate suppliers.
- Implement robust quality control measures.
- Monitor market conditions regularly.
- Maintain appropriate inventory levels.
- Stay informed about regulatory requirements.
As a bulk disodium guanylate manufacturer and supplier in China, we supply high-quality disodium guanylate E627 to large food manufacturers and beverage companies worldwide. We also wholesale our disodium guanylate to small customers. Normally, they want to buy disodium guanylate in small quantities. To serve them, we can wholesale disodium guanylate at bulk prices and provide a one-stop purchasing service.
Disodium Guanylate Prices (USD/Kg)
Food Grade Disodium Guanylate Price (Purity: 97.0%–101.0%)
| Volume | Unit Price | Shipment |
| 50g | 10 USD | Express |
| 500g | 30USD | Express |
| 1Kg | 42 USD /Kg | Express |
| 20Kg | 20% cheaper | Express |
| 100Kg-Above | negotiable | Express / Sea |
Disodium guanylate (E627) has seen significant price fluctuations in the global market throughout recent years. Disodium guanylate prices are influenced by multiple factors, including raw material costs, shipping rates, and market demand. Disodium guanylate buyers should consider not only the base price but also shipping methods, order volumes, and quality requirements. The total landed cost of disodium guanylate can vary significantly based on these factors, making it essential to evaluate multiple suppliers and logistics options for optimal value.
Furthermore, the above price quotations of disodium guanylate, especially for small orders, do not include the express shipping fee. The reason is that the shipment cost of disodium guanylate E627 may exceed the value of the sample. But the bulk wholesale prices of disodium guanylate will be much lower than those of small orders. Bulk orders exceeding 1000 kg will receive preferential pricing. Please contact us for more details.
Disodium Guanylate Uses
Disodium guanylate E627 is widely used in various industries:
Food Industry
- Instant noodles
- Snack foods
- Convenience meals
- Seasonings and condiments
Commercial Food Service
- Restaurant seasonings
- Industrial food preparation
- Institutional cooking
Disodium Guanylate Benefits
The primary benefits of using disodium guanylate include:
Flavor Enhancement
- Intensifies umami taste
- Reduces salt usage
- Improves overall flavor profile
Technical Benefits
- Excellent stability
- Good solubility
- Synergistic effect with other flavor enhancers
- Cost-effective in application
Disodium Guanylate Used in Food and Feed
A Fish Cake Suitable for Children – Formulation by Weight
Ingredients by weight: Fish paste, 50 parts; Egg white, 5 parts; Carrot cubes, 5 parts; Starch, 12 parts; Salt, 3 parts; Vinegar, 1.2 parts; Monosodium glutamate, 3 parts; Honey, 3 parts; Citric acid, 0.2 parts; Disodium guanylate, 0.1 parts and Drinking water containing lemon juice, 11 parts.
A Composite Seasoning Feed Granules – Formulation by Weight
Ingredients include (per 100 kg feed):
Glutamine, 6kg; Disodium guanylate, 9kg; Disodium 5′-inosinate, 6kg; γ-Aminobutyric acid, 5kg; Stevia extract, 6kg; Carboxymethyl chitosan, 2kg; Glycine iron, 0.15kg; Flavor mixture, 3kg; Corn flour, 62.85kg.
Production method:
Accurately weigh the raw materials according to this formula, put the raw materials into the powder mixer, add warm water at a uniform speed, and stir until they are evenly distributed. The mixed materials are transported to the semi-automatic pellet filling machine by the elevator to produce the seasoning pellets of the required particle size, and the pellets are transported to the oven for baking by the air conveyor. After baking, they are transported to the oil sprayer by the elevator for oil spraying. After the oil spraying, they are cooled and transported. Finally, the pellets are put into the vibrating screen to screen out the excess external materials and pellet fragments, and then packaged.
In conclusion, disodium guanylate continues to play a crucial role in the food industry as a flavor enhancer. Its stable supply chain, established manufacturing processes, and proven benefits make it an important ingredient in modern food processing. As a bulk disodium guanylate manufacturer and supplier in China, Sinofi sells different grades of disodium guanylate at wholesale prices to large manufacturers and small customers worldwide.