This section focuses on an overview of sodium methylparaben powder as well as its manufacturing processes and uses. Also, please check out the introduction to sodium methylparaben manufacturers, supply chain issues, sodium methylparaben suppliers, and sodium methylparaben prices. Sinofi can help you buy high-quality sodium methylparaben in bulk for your industry applications at wholesale prices based on E219 and CAS 5026-62-0.
Table of Contents
What is Sodium Methylparaben?
Sodium methylparaben is a widely used preservative in the pharmaceutical, cosmetic, and food industries. It serves as an antimicrobial agent that helps extend the shelf life of various products by preventing the growth of harmful microorganisms. Sodium methylparaben belongs to a class of compounds known as parabens, which are esters of para-hydroxybenzoic acid. According to the U.S. Food and Drug Administration (FDA), sodium methylparaben is approved to be used in the food and pharmaceutical industries.
CAS No.: 5026-62-0
According to the American Chemical Society, the CAS number of sodium methylparaben is 5026-62-0.
Molecular Formula: C8H8O3.Na
Molecular Mass: 175.14
Appearance: White crystalline powder
Solubility: Freely soluble in water, sparingly soluble in ethanol.
Other Names:
Sodium methylparaben
Sodium methyl p-hydroxybenzoate
Methyl p-hydroxybenzoate sodium salt
Methyl 4-hydroxybenzoate sodium salt
p-Hydroxybenzoic acid methyl ester sodium salt
Sodium 4-carbomethoxyphenolate
Methylparaben sodium
Sodium methyl 4-hydroxybenzoate
Sodium p-methoxycarbonylphenolate
Sodium methyl para-hydroxybenzoate
Sodium nipagin
Sodium 4-(methoxycarbonyl)phenolate
Nipagin Monosodium
Nipagin MNA
E number: E219
According to the European Food Safety Authority (EFSA), sodium methylparaben is approved to be used as food additive E219.
Bulk Sodium Methylparaben Manufacturers
The sodium methylparaben production capacity has grown steadily over the past decade, driven by increasing demand from personal care, pharmaceutical, and food preservation applications. It is dominated by several bulk sodium methylparaben manufacturers like Sharon Laboratories and Ueno Fine Chemicals. These manufacturers maintain sophisticated production facilities that adhere to strict quality standards and good manufacturing practices.
Sinofi is a bulk sodium methylparaben manufacturer in China, and we have a manufacturing facility with 2,500 square meters for the production of sodium methylparaben E219. We supply high-quality sodium methylparaben at bulk prices and serve the food, pharmaceutical, cosmetics, and personal care industries worldwide.
Manufacturing Process of Sodium Methylparaben
Raw Materials
The primary raw materials required for sodium methylparaben production include:
• Methyl 4-hydroxybenzoate (methylparaben)
• Sodium hydroxide (NaOH)
• Purified water
• Additional process aids and purification materials
Manufacturing Process
Raw Material Preparation
The process begins with the careful preparation of raw materials. Methylparaben, the primary starting material, must meet specific quality requirements, including a minimum purity of 99%. A precise sodium hydroxide solution is prepared using purified water under controlled conditions to ensure accurate concentration.
Neutralization Reaction
The core manufacturing step involves the neutralization reaction between methylparaben and sodium hydroxide. This reaction is conducted in a temperature-controlled reactor vessel at 25-30°C. The stoichiometric ratio of methylparaben to sodium hydroxide is carefully maintained to ensure complete conversion while avoiding excess alkali.
Crystallization
Following the neutralization reaction, the solution undergoes controlled crystallization. The temperature is gradually reduced to 10-15°C to promote crystal formation. This step is critical for achieving the desired particle size distribution and crystal morphology.
Solid-Liquid Separation
The crystallized sodium methylparaben is separated from the mother liquor using centrifugation or filtration equipment.
Drying
The wet sodium methylparaben undergoes drying in a fluid bed dryer or vacuum tray dryer.
The successful manufacture of sodium methylparaben requires precise control of process parameters, adherence to quality standards, and comprehensive documentation. Understanding and maintaining these critical aspects ensures consistent production of high-quality sodium methylparaben suitable for various industrial applications.
Bulk Sodium Methylparaben Suppliers
The global sodium methylparaben supply is dominated by bulk suppliers in Asia, particularly China, with significant operations also present in Europe and North America. Top sodium methylparaben suppliers include Sharon Laboratories and Ueno Fine Chemicals. Ueno Fine Chemicals Industry, headquartered in Japan, stands as one of the most respected producers, known for its high-quality standards and reliable supply chain. Sharon Laboratories, based in Israel, has established itself as another premier supplier, particularly strong in serving the cosmetics industry.
Sinofi is a bulk sodium methylparaben supplier in China, and we have a warehouse with 1,200 square meters for high-quality sodium methylparaben E219. We sell different grades of sodium methylparaben at wholesale prices to food, pharmaceutical, cosmetics, and personal care manufacturers.
Supply Chain of Sodium Methylparaben
The sodium methylparaben supply chain represents a complex global network that continues to adapt to changing market demands, regulatory requirements, and technological capabilities.
Supply Chain Structure
Raw Material Sourcing
The production of sodium methylparaben begins with the sourcing of key raw materials, primarily para-hydroxybenzoic acid (PHBA) and methanol. PHBA is predominantly manufactured in China and India, with several major chemical companies controlling most of the global production.
Manufacturing
The manufacturing process involves several stages:
- Primary Production: The esterification of PHBA with methanol produces methylparaben.
- Secondary Processing: Methylparaben is converted to its sodium salt form.
- Purification and Quality Control: The final product undergoes rigorous testing to meet regulatory standards.
Distribution Network
The distribution network consists of multiple tiers:
- Primary Distributors: Large chemical distribution companies that handle bulk quantities.
- Regional Distributors: Mid-sized companies serving specific geographic markets.
- Local Distributors: Smaller companies supplying end-users in specific industries.
End-User Industries
The main end-user segments include:
- Cosmetics and Personal Care (45% of consumption)
- Pharmaceuticals (30% of consumption)
- Food and Beverages (15% of consumption)
- Others (10% of consumption)
Success in this market requires careful attention to quality control, regulatory compliance, and efficient distribution systems, while also embracing emerging trends in sustainability and digitalization.
Wholesale and Buy Sodium Methylparaben in Bulk
Successful wholesale procurement of sodium methylparaben requires careful attention to quality, regulatory compliance, and proper handling procedures. Sodium methylparaben buyers should establish relationships with reliable suppliers while maintaining robust safety and documentation practices.
When sourcing sodium methylparaben wholesale, buyers should prioritize:
Certification Requirements
Ensure the supplier provides appropriate documentation, including certificates of analysis, safety data sheets, and compliance with relevant regulations like FDA or EU standards.
Supplier Evaluation
Work with reputable chemical suppliers who maintain good manufacturing practices certification and can provide consistent quality across bulk orders.
As a bulk sodium methylparaben manufacturer and supplier in China, we supply high-quality ingredients for the food, pharmaceutical, cosmetics, and personal care industries. We also wholesale sodium methylparaben to small customers. Normally, they want to buy sodium methylparaben powder in small quantities. To serve them, we can wholesale high-quality sodium methylparaben at bulk prices and provide a one-stop purchasing service.
Sodium Methylparaben Prices (USD/Kg)
Food Grade Sodium Methylparaben Prices (Purity = 99.0%–101.5%)
| Volume | Unit Price | Shipment |
| 50g | 8 USD | Express |
| 500g | 28 USD | Express |
| 1Kg | 45 USD /Kg | Express |
| 20Kg | 20% cheaper | Express |
| 100Kg-Above | negotiable | Express / Sea |
Sodium methylparaben prices have experienced notable fluctuations across major manufacturing regions, driven by shifting supply chain dynamics and evolving regulatory landscapes. Bulk sodium methylparaben manufacturers have maintained steady production levels, though increased environmental regulations have impacted operational costs. Demand remains robust from the cosmetics and pharmaceutical sectors.
Bulk sodium methylparaben prices fluctuate based on several factors:
- Raw material costs, particularly 4-hydroxybenzoic acid.
- Energy prices affecting production costs.
- Transportation costs.
- Order volume and term commitments.
- Regional market conditions.
Furthermore, the above sodium methylparaben price quotations, especially for small orders, do not include the express shipping fee. This is because the shipment cost of sodium methylparaben may exceed the value of the sample. However, the bulk wholesale prices of sodium methylparaben will be much lower than those of small orders. Please contact us for more details.
Sodium Methylparaben Uses
Cosmetics and Personal Care Uses
In the cosmetics industry, sodium methylparaben serves as a primary preservative in various products. Its effectiveness in preventing microbial growth helps maintain product stability and safety in:
- Facial creams and moisturizers
- Makeup foundations and concealers
- Hair care products
- Body lotions and sunscreens
The compound’s ability to dissolve readily in water-based formulations makes it particularly valuable for these applications, typically used at concentrations between 0.1% and 0.4%.
Food Uses
While less common than in personal care products, sodium methylparaben finds applications in the food industry as preservative E219, particularly in:
- Processed beverages
- Baked goods
- Preserved fruits and vegetables
- Confectionery products
Pharmaceutical Uses
The pharmaceutical sector extensively utilizes sodium methylparaben for its preservative properties in:
- Oral medications and syrups
- Injectable solutions
- Topical medications
- Over-the-counter drugs
Its broad-spectrum antimicrobial activity helps maintain drug stability and prevents contamination throughout the product’s shelf life.
Sodium Methylparaben Benefits
The primary advantages of sodium methylparaben include its broad-spectrum antimicrobial activity, cost-effectiveness, and stability across various pH levels. It performs particularly well in neutral to slightly acidic conditions and remains effective even at elevated temperatures.
Enhanced Antimicrobial Benefits
Broad-Spectrum Activity
One of sodium methylparaben’s primary advantages lies in its comprehensive antimicrobial protection. The compound demonstrates remarkable effectiveness against:
- Various species of bacteria, including both gram-positive and gram-negative strains.
- Multiple fungi species are commonly associated with product contamination.
- Yeasts that often compromise product integrity.
This broad-spectrum activity ensures robust preservation across diverse formulation types, maintaining product safety throughout its intended shelf life.
Stability Across Conditions
The compound maintains its antimicrobial efficacy across varying environmental conditions, providing:
- Consistent performance across a wide pH range (4-8).
- Stability at elevated temperatures during processing.
- Continued effectiveness throughout typical storage conditions.
- Resilience in the presence of other formulation ingredients.
Formulation Benefits
Superior Water Solubility
The sodium salt form of methylparaben offers enhanced water solubility compared to its parent compound, delivering several key benefits:
- Easier incorporation into aqueous systems
- More uniform distribution throughout the formulation
- Reduced processing time during manufacturing
- Greater flexibility in formulation development
Compatibility Profile
The compound demonstrates excellent compatibility with a wide range of ingredients commonly used in various formulations:
- Surfactants and emulsifiers
- Active ingredients in pharmaceutical preparations
- Coloring agents and fragrances
- Various packaging materials
Economic Benefits
Cost-Effectiveness
From a business perspective, sodium methylparaben offers significant economic advantages:
- Lower usage levels are required for effective preservation
- Reduced manufacturing costs due to easy incorporation
- Extended shelf life leading to decreased product waste
- Competitive pricing compared to alternative preservatives
Processing Efficiency
The compound’s properties contribute to manufacturing efficiency through:
- Simplified mixing procedures
- Reduced energy requirements during processing
- Minimal additional equipment needs
- Streamlined quality control processes
Product Performance Benefits
Sensory Characteristics
The compound’s neutral profile contributes positively to final product characteristics:
- No impact on product color
- Minimal effect on odor
- No influence on product texture
- No interference with active ingredients
Stability Enhancement
Beyond its preservative function, sodium methylparaben contributes to overall product stability:
- Helps maintain product integrity throughout shelf life
- Supports consistency in product performance
- Aids in maintaining aesthetic qualities
- Contributes to formula stability
Sodium methylparaben’s numerous benefits make it an invaluable ingredient in modern formulations. Its combination of effective preservation, formulation advantages, and economic benefits makes it a strategic choice for manufacturers across various industries.
Sodium Methylparaben Used in Cosmetics
A Cosmetic Preservative and Its Preparation Method
The components, by mass percentage, include natamycin 0.08%, sodium methylparaben 1%, methylbenzyl glycol 2%, citric acid 2%, and the rest is pure water.
The preparation method:
1) Add natamycin, sodium methylparaben, and methylbenzyl glycol to water and stir; set aside.
2) Add citric acid to the solution from step 1), stir evenly, and the final preservative is obtained.
In conclusion, sodium methylparaben continues to play a vital role in the food, pharmaceutical, cosmetics, and personal care industries. As a bulk sodium methylparaben manufacturer and supplier in China, we sell different grades of sodium methylparaben at wholesale prices to large manufacturers and small customers worldwide.