This section focuses on an overview of cooling agent WS-10 (menthoxypropanediol or Symcool WS-10) as well as its manufacturing processes and uses. Also, please check out the introduction to menthoxypropanediol WS-10 manufacturers, supply chain issues, menthoxypropanediol WS-10 suppliers, and menthoxypropanediol WS-10 prices. Sinofi can help you buy high-quality menthoxypropanediol WS-10 in bulk for your industry applications at wholesale prices based on FEMA 3784 and CAS 87061-04-9.
Table of Contents
What is Menthoxypropanediol WS-10?
WS-10, also known as menthoxypropanediol or Symcool WS-10, is a synthetic cooling agent widely used in personal care products, cosmetics, and oral care formulations. WS-10 belongs to a family of compounds called carboxamides, including WS-3, WS-5, and WS-23. It works by activating the TRPM8 receptors in the skin, creating a sensation of coolness without actual temperature change. Menthoxypropanediol WS-10 consists of a menthol molecule attached to a propanediol group, which enhances its stability and modifies its sensory profile. According to the U.S. Food and Drug Administration (FDA), menthoxypropanediol WS-10 is approved to be used in the food, cosmetics, and pharmaceutical industries. It has also been evaluated by relevant regulatory authorities like JECFA, EUR-Lex, ECHACHEM, and WHO. The IFRA Transparency List provides a guideline to ensure the use of menthoxypropanediol WS-10 in the pharmaceutical and cosmetic industries.
CAS No.: 87061-04-9
According to the American Chemical Society, the CAS number of menthoxypropanediol WS-10 is 87061-04-9.
CAS Name: 3-((L-Menthyl)oxy)propane-1,2-diol
Molecular Formula: C13H26O3
Molecular Mass: 230.34
Appearance: Colorless to pale yellow liquid
Solubility: Easily soluble in alcohol; very slightly soluble in water: 108.1 mg/L @ 25 °C (est)
Other Names:
♦ Symcool WS-10
♦ TK 10
♦ Cooling agent 10
♦ Cooling Agent WS-10
♦ 3-[[5-Methyl-2-(1-methylethyl)cyclohexyl]oxy]-1,2-propanediol
FEMA Number 3784
According to the Flavor and Extract Manufacturers Association (FEMA), the number of menthoxypropanediol WS-10 is FEMA 3784.
Bulk Menthoxypropanediol WS-10 Manufacturers
The global production of menthoxypropanediol WS-10 is primarily concentrated in Germany, Japan, and China. Top menthoxypropanediol WS-10 manufacturers like Symrise are the earliest developers of cooling agents, with significant production capacity and technical expertise.
Sinofi is a bulk manufacturer of menthoxypropanediol WS-10 in China, and we have a manufacturing facility with 2,500 square meters for the production of Symcool WS-10. We supply high-quality menthoxypropanediol WS-10 at bulk prices and serve the food, pharmaceutical, cosmetics, and personal care industries worldwide.
Manufacturing Process of Menthoxypropanediol WS-10
The production of menthoxypropanediol WS-10 typically involves multi-step organic synthesis processes conducted in specialized chemical manufacturing facilities.
Menthol reacts with glycidol to obtain L-menthoxypropanediol. The reaction temperature is the reflux temperature. The reaction time is 8-10 hours. The solvents used in the reaction are toluene, benzene, and xylene. The catalysts used in the reaction are tin chloride, boron trifluoride ether, etc.
Bulk Menthoxypropanediol WS-10 Suppliers
The global supply of menthoxypropanediol WS-10 is dominated by bulk suppliers like Symrise AG and some companies in China and Japan. They are bulk manufacturers with dedicated manufacturing facilities. Asian menthoxypropanediol WS-10 suppliers offer competitive pricing, while European and North American suppliers often provide enhanced documentation and regulatory support.
Sinofi is a bulk menthoxypropanediol WS-10 supplier in China, and we have a warehouse with 1,200 square meters for high-quality WS-10 cooling agent. We sell different grades of WS-10 at wholesale prices to food, pharmaceutical, cosmetics, and personal care manufacturers.
Supply Chain of Menthoxypropanediol WS-10
Raw Material Production
The WS-10 supply chain begins with the sourcing of key chemical precursors, primarily menthol. Menthol is typically extracted from cultivated mint plants (primarily Mentha arvensis) grown in major producing regions, including India, China, and parts of South America. Synthetic routes for menthol production also exist, with companies like BASF.
Supply Chain Structure
The WS-10 supply chain follows a multi-tiered model:
- Raw Material Suppliers: Agricultural producers (mint farmers) and basic chemical manufacturers providing raw materials.
- WS-10 Manufacturers: Specialty chemical companies synthesizing menthoxypropanediol WS-10.
- WS-10 Suppliers: Formulation specialists and ingredient distributors like Univar Solutions, Brenntag..
- WS-10 Key Accounts: Cosmetic and personal care product manufacturers.
- WS-10 Retailers: Channels delivering final products to consumers.
The Asia-Pacific region, particularly China and Japan, dominates both production and consumption of Symcool WS-10, though European and North American markets have seen steady growth in recent years. Regional distributors also play crucial roles in connecting manufacturers with formulators in specific markets.
Wholesale and Buy Menthoxypropanediol WS-10 in Bulk
By purchasing in bulk, menthoxypropanediol WS-10 buyers can secure cost advantages while ensuring consistent quality and supply chain reliability. It offers significant cost savings through:
- Volume discounts from suppliers.
- Reduced shipping costs per unit.
- Lower processing fees for fewer, larger transactions.
Menthoxypropanediol WS-10 represents an important ingredient for manufacturers looking to incorporate cooling sensations into their product lines. When you are selecting a Symcool WS-10 supplier, please consider your specific application requirements, required certifications, and total supply chain costs rather than focusing solely on per-kilogram pricing. The right supplier partnership can significantly impact both product quality and operational efficiency.
Identifying Reliable Suppliers
When searching for menthoxypropanediol WS-10 suppliers, prioritize companies that:
- Provide comprehensive certificates of analysis.
- Have transparent manufacturing processes.
- Offer consistent purity levels (typically 98% or higher).
- Can supply necessary regulatory documentation.
Regulatory Considerations
Before purchasing WS-10 in bulk, verify:
- Compliance with local food and cosmetic ingredient regulations.
- Proper documentation for import/export for purchasing internationally.
- Safety data sheets and handling protocols.
- All required licenses for purchasing chemical ingredients.
As a bulk manufacturer and supplier of menthoxypropanediol WS-10 in China, we supply high-quality WS-10 cooling agent for food, pharmaceutical, cosmetics, and personal care industries. We also wholesale WS-10 to small customers. Normally, they want to buy menthoxypropanediol WS-10 in small quantities. To serve them, we can wholesale cooling agent WS-10 at bulk prices and provide a one-stop purchasing service.
Menthoxypropanediol WS-10 Prices (USD/Kg)
Food Grade Cooling Agent Menthoxypropanediol WS-10 Prices (purity >=99.0%)
| Volume | Unit Price | Shipment |
| 50g | 22 USD | Express |
| 500g | 140 USD | Express |
| 1Kg | 190 USD/Kg | Express |
| 20Kg | 30% cheaper | Express |
| 100Kg-Above | negotiable | Express / Sea |
Bulk menthoxypropanediol WS-10 prices typically range between $180-200 per kilogram for food, cosmetic, and pharmaceutical grades, depending on volume, purity, and supplier relationships. This represents a moderate increase of approximately 7-10% from 2023 prices, attributed primarily to increased demand rather than production constraints.
Key pricing factors include:
- Purity levels: Higher purity grades (99%+) command premium pricing.
- Order volume: Bulk orders (500+ kg) typically receive 15-20% discounts.
- Regional variations: Asian manufacturers generally offer more competitive pricing compared to European or North American suppliers.
WS-10 prices are expected to stabilize in the following years, with potential modest increases of 3-5% annually based on:
- Growing adoption in premium skincare formulations..
- Expanded applications in pharmaceutical cooling products.
- Continued consumer preference for longer-lasting cooling sensations.
Furthermore, the above price quotations of menthoxypropanediol WS-10, especially for small orders, do not include the express shipping fee. The reason is that the shipment cost of WS-10 cooling agent may exceed the value of the sample. However, the bulk wholesale prices of menthoxypropanediol WS-10 will be much lower than those of small orders. Please contact us for more details.
Menthoxypropanediol WS-10 Uses
Menthoxypropanediol, commonly known as Symcool WS-10, is a synthetic cooling agent that has gained significant popularity in various industries.
Food and Beverage Uses
Though less common than its cosmetic applications, Symcool WS-10 is also found in certain food and beverage products:
- Specialty candies and confections.
- Premium alcoholic beverages.
- Flavored water and sports drinks.
- Functional foods with refreshing properties.
Cosmetic and Personal Care Uses
WS-10 has become a staple ingredient in the personal care industry due to its distinctive cooling properties. Unlike menthol, which can sometimes irritate, Symcool WS-10 provides a milder, longer-lasting cooling effect without the strong minty odor.
Common cosmetic applications include:
- Facial cleansers and toners that deliver a refreshing sensation.
- After-sun products that soothe and cool the skin.
- Anti-aging products where the cooling effect helps reduce the appearance of puffiness.
- Lip balms and glosses that provide a pleasant tingling sensation.
Oral Care Uses
The oral care industry has embraced WS-10 for its ability to enhance the cooling sensation in:
- Mouthwashes and breath fresheners
- Toothpastes and tooth whitening systems
- Dental rinses and oral sprays
- Sugar-free chewing gums and mints
What makes WS-10 particularly valuable in oral care is its sustainability—the cooling effect lasts significantly longer than traditional cooling agents.
Pharmaceutical Uses
In the pharmaceutical sector, WS-10 is utilized in various formulations:
- Topical analgesics for muscle and joint pain
- Anti-itch creams and lotions
- Nasal decongestants
- Throat lozenges and sprays
The compound’s cooling effect helps create a sensation of relief without affecting the active medicinal ingredients.
Menthoxypropanediol WS-10 Benefits
Superior Cooling Benefits
WS-10 provides a more intense and longer-lasting cooling effect compared to traditional menthol. The cooling sensation it delivers is often described as “cleaner” and less harsh than menthol, creating a more pleasant user experience in products where a refreshing sensation is desired.
Stability Benefits
One of the most significant advantages of WS-10 is its excellent stability across various formulation types. Unlike some cooling agents that can degrade or lose potency over time, WS-10 maintains its cooling properties throughout a product’s shelf life, ensuring consistent performance.
Versatility in Formulations
Menthoxypropanediol works effectively across a wide range of product types, including:
- Facial cleansers and masks
- After-sun care products
- Muscle relief gels and creams
- Oral care products
- Hair care formulations
- Foot care products
Lower Irritation Benefits
For many consumers with sensitive skin, traditional menthol can cause irritation or discomfort. WS-10 typically offers a gentler cooling effect with less potential for irritation, making it suitable for a broader range of skin types.
No Strong Odor
Unlike menthol, which has a distinctive minty scent that can conflict with product fragrances, WS-10 is virtually odorless. This property gives formulators greater flexibility in creating products with specific fragrance profiles without interference.
As consumer demand for multi-sensory products continues to grow, menthoxypropanediol WS-10 is likely to play an increasingly important role in product development.
Menthoxypropanediol WS-10 Used in Cosmetics
A Method for Preparing Cooling Wet Wipes
Include the following preparation steps:
Dissolve 0.05% cetylpyridinium chloride in 6 times its mass of 50°C pure water and mix evenly, then add it to 83.04% EDI purified water and mix, cool naturally to room temperature, then add 0.1% zinc phenolsulfonate, 15% ethanol, 0.1% 3-methyl-4-isopropylphenol, stir at 300r/min for 30min, then add 0.1% propylene glycol, 1% menthol, 0.04% borneol, 0.5% PEG-40 hydrogenated castor oil, heat to 50°C, continue stirring for 30min, cool naturally to room temperature, add 0.02% menthoxypropanediol WS-10 and 0.05% citric acid, stir them at 200r/min for 30min, then get the cooling solution.
Impregnate or spray the cooling solution on the dry base cloth. The mass of the cooling solution is 4 times that of the dry base cloth. Then get the final cooling wet wipe.
In conclusion, menthoxypropanediol WS-10 is gaining significant traction among manufacturers of food, personal care, and cosmetics. This cooling agent offers a unique profile that makes it valuable for a variety of applications requiring a refreshing sensation without the harshness associated with traditional menthol. As a bulk manufacturer and supplier of menthoxypropanediol WS-10 in China, we sell different grades of Symcool WS-10 at wholesale prices to large manufacturers and small customers worldwide.