This section focuses on an overview of fructone (apple ketal) as well as its manufacturing processes and uses. Also, please check out the introduction to apple ketal fructone manufacturers, supply chain issues, fructone suppliers, and fructone prices. Sinofi can help you buy high-quality apple ketal fructone in bulk for industry applications at wholesale prices based on FEMA 4477 and CAS 6413-10-1.
Table of Contents
What is Fructone?
Fructone, also known as apple ketal or applinal, is a fascinating organic compound that plays a significant role in the fragrance and flavor industries. Known for its distinctive fruity aroma, this cyclic ketone has captured the attention of chemists, perfumers, and food scientists worldwide. Despite its relatively simple molecular structure, fructone’s unique olfactory properties make it an invaluable ingredient in creating complex scent profiles and flavor compositions. Fructone, chemically known as ethyl acetoacetate ethyleneglycol ketal, belongs to the family of α,β-unsaturated ketones. It features a five-membered ring structure with a ketone functional group and a methyl substituent. This specific arrangement of atoms is responsible for its characteristic sweet, fruity odor that resembles strawberries, peaches, or tropical fruits. According to the U.S. Food and Drug Administration (FDA), apple ketal fructone is approved to be used in the food, flavour, fragrance, personal care, and cosmetic industries. It has also been evaluated by relevant regulatory authorities like JECFA, EUR-Lex, ECHACHEM, NIST, RIFM, and WHO. The IFRA provides a guideline to ensure the use of fructone in the food, flavour, fragrance, personal care, and cosmetic industries.
Sensory Characteristics
The sensory profile of fructone is what makes it so valuable across industries. Trained sensory panels describe its odor as:
Sweet and fruity with strawberry-like nuances
• Fresh and natural-smelling rather than artificial
• Relatively stable and long-lasting
• Harmonious when blended with other aromatic compounds
The compound’s relatively low odor threshold means that even small concentrations can produce noticeable effects, making it cost-effective for commercial applications.
Safety and Regulatory Considerations
Fructone has undergone extensive safety testing and is generally recognized as safe (GRAS) for use in food applications by regulatory authorities in many countries. The compound has been evaluated for:
- Toxicological Safety: Studies have shown low acute toxicity levels, with no significant adverse effects observed at typical usage concentrations.
- Allergenicity: Unlike some fragrance compounds, fructone is not classified as a common allergen, though sensitive individuals may still experience reactions.
- Environmental Impact: The compound is biodegradable and does not persist in the environment, making it environmentally acceptable for commercial use.
CAS No.: 6413-10-1
According to the American Chemical Society, the CAS number of apple ketal fructone is 6413-10-1.
CAS Name: Ethyl Acetoacetate Ethylene Ketal
Molecular Formula: C8H14O4
Molecular Mass: 174.19
Appearance: Colorless, clear liquid
Boiling Point: 125.00 to 126.00 °C. @ 760.00 mm Hg
Solubility: Soluble in alcohol, slightly soluble in water (100 mg/L @ 20 °C)
Other Names:
♦ apple ketal
♦ fructone
♦ ethyl acetoacetate ethylene glycol ketal
♦ 1,3-dioxolane-2-acetic acid, 2-methyl-, ethyl ester
♦ ethyl 2-methyl-1,3-dioxolane-2-acetate
Fructone Odor
Odor Strength: Medium
Substantivity: 12 hours at 100.00 %
At 100.00 %. sweet fruity apple green tropical plum woody.
FEMA Number 4477
According to the Flavor and Extract Manufacturers Association (FEMA), the number of apple ketal fructone is FEMA 4477.
Bulk Fructone Manufacturers
The bulk manufacturing of apple ketal fructone is dominated by several global aromatic chemical companies that operate large-scale production facilities. Top apple ketal fructone manufacturers like International Flavors & Fragrances stand as the world’s leading fragrance and flavor manufacturers, with significant fructone production capabilities. Their extensive research and development facilities enable continuous innovation in synthetic aromatic compounds. Asian apple ketal fructone manufacturers, particularly those based in China, have gained considerable market share in recent years due to competitive pricing and improved quality standards.
Sinofi is a bulk manufacturer of apple ketal fructone in China, and we have a manufacturing facility with 2,500 square meters for the production of ethyl acetoacetate ethylene ketal. We supply high-quality apple ketal fructone at bulk prices and serve food, flavour, fragrance, personal care, and cosmetic industries worldwide.
Manufacturing Process of Fructone
Fructone manufacturing represents a sophisticated intersection of chemistry and engineering, producing essential ingredients that enhance countless consumer products.
Chemical Synthesis Method
Raw materials: ethyl acetoacetate (purity ≥98%); ethylene glycol (purity≥99%).
Catalyst: concentrated sulfuric acid (purity ≥98%).
Production Method
Ethyl acetoacetate is added to the reaction vessel, and then ethylene glycol is added under stirring (stirring speed is 150 rpm). Stirring can make the reactants fully mixed, so that the reaction can be completed quickly. Then, concentrated sulfuric acid is slowly added while stirring after the addition of ethylene glycol. At this time, the initial reaction temperature is 30°C, and the temperature reaches 44°C after the addition of concentrated sulfuric acid. In actual production, the reaction can be carried out at normal ambient temperature, and it is not necessary to heat or cool to 30 degrees. Continue stirring, keep reacting for 1 hour, and then stand still until the feed liquid is divided into upper and lower layers. The upper layer is a mixture of ethyl acetoacetate and crude fructone, and the lower layer is a mixture of ethylene glycol, concentrated sulfuric acid, and water. After separating the upper mixture, wash and fractionate it to obtain the final fructone.
As technology advances and sustainability becomes increasingly important, the industry continues evolving to meet changing market demands while maintaining the quality and consistency that make these compounds indispensable in modern manufacturing.
Bulk Fructone Suppliers
The bulk supply of apple ketal fructone is characterized by a mix of large multinational chemical companies and specialized fragrance and flavor ingredient suppliers. Top apple ketal fructone suppliers like International Flavors & Fragrances lead the bulk market, leveraging their extensive manufacturing capabilities, global distribution networks, and established relationships with major brands. These suppliers typically offer competitive pricing for large-volume orders and maintain consistent quality standards across multiple production facilities.
Sinofi is a bulk apple ketal fructone supplier in China, and we have a warehouse with 1,200 square meters for high-quality apple ketal. We sell different grades of fructone at wholesale prices to food, flavour, fragrance, personal care, and cosmetic manufacturers.
Supply Chain of Fructone
The fructone supply chain represents a complex network of interconnected processes, stakeholders, and distribution channels that ensure the reliable delivery of this important ingredient from production facilities to end consumers.
Supply Chain Structure Overview
Raw Material Suppliers
The fructone supply chain begins with raw materials suppliers: ethyl acetoacetate and ethylene glycol.
Processing and Manufacturing
Fructone manufacturers involve the transformation of raw materials into fructone through various chemical processing methods.
Distribution and Logistics
The distribution network forms the backbone of fructone delivery to end users:
- Primary Distributors: Large-scale distribution companies that handle bulk quantities.
- Regional Suppliers: These companies are strategically located to serve specific geographic markets.
End Users
The end users incorporate fructone into their finished products.
Success in the fructone market requires careful attention to quality management, regulatory compliance, and supply chain optimization while adapting to evolving industrial demands and technological capabilities.
Wholesale and Buy Fructone in Bulk
Wholesale purchasing of fructone offers significant opportunities for cost savings and operational efficiency for buyers in the fragrance and flavor industries. Success requires careful attention to fructone supplier selection, quality management, storage requirements, and risk mitigation strategies. By implementing best practices in bulk procurement, apple ketal fructone buyers can achieve sustainable competitive advantages while ensuring reliable access to this essential aromatic compound.
Benefits of Wholesale and Bulk Purchasing
Cost Advantages
Purchasing fructone in bulk quantities offers significant economic benefits.
Volume Discounts
Suppliers typically offer substantial price reductions for large orders, with savings often ranging from 15-40% compared to smaller quantities.
Reduced Per-Unit Costs
The cost per kilogram or pound decreases dramatically as order sizes increase, improving overall profit margins.
Shipping Efficiency
Bulk orders reduce the frequency of shipments, lowering transportation costs and minimizing logistics expenses.
As a bulk manufacturer and supplier of apple ketal fructone in China, we supply high-quality fructone for food, flavour, fragrance, personal care, and cosmetic industries. We also wholesale apple ketal to small customers. Normally, they want to buy fructone in small quantities. To serve them, we can wholesale fructone at bulk prices and provide a one-stop purchasing service.
Fructone Prices (USD/Kg)
Food Grade Fructone Prices (FCC, GC Content >=98.0%)
| Volume | Unit Price | Shipment |
| 50g | 10 USD | Express |
| 500g | 45 USD | Express |
| 1Kg | 65 USD/Kg | Express |
| 20Kg | 20% cheaper | Express |
| 100Kg-Above | negotiable | Express / Sea |
The apple ketal fructone prices have experienced notable volatility in recent years. Currently, fructone commands premium pricing due to its specialized applications and the complexity of its production processes. Market analysis indicates that fructone prices typically range from moderate to high levels compared to standard chemical intermediates, primarily due to the sophisticated manufacturing requirements and relatively limited production capacity globally. The compound’s unique properties make it particularly valuable in high-end applications, justifying its premium market position.
Key Factors Influencing Fructone Pricing
Raw Material Costs
The primary driver of fructone pricing lies in the cost and availability of its precursor materials.
Manufacturing Complexity
Fructone production involves sophisticated chemical processes that require specialized equipment, controlled environments, and skilled personnel. The technical complexity of synthesis, purification, and quality control procedures contributes significantly to the overall cost structure. Manufacturing facilities must maintain strict quality standards, particularly for food-grade applications, adding to operational expenses.
Regulatory Environment
The regulatory landscape surrounding fructone varies significantly across different regions and applications. Compliance with food safety regulations, environmental standards, and chemical registration requirements impacts both production costs and market access. Recent regulatory changes in major markets have introduced additional compliance costs that manufacturers typically pass on to customers.
Supply Chain Dynamics
The fructone market is characterized by a relatively concentrated supplier base, with a limited number of manufacturers capable of producing high-quality material at a commercial scale. This supply concentration can lead to price sensitivity during periods of high demand or supply disruptions. Transportation costs, storage requirements, and inventory management also influence final pricing.
Furthermore, the above price quotations of apple ketal fructone, especially for small orders, do not include the express shipping fee. The reason is that the shipment cost of apple ketal fructone may exceed the value of the sample. However, the bulk wholesale fructone prices will be much lower than those of small orders. Please contact us for more details.
Fructone Uses
Perfumery Uses
Apple ketal fructone has found some use in perfume compositions where a certain deep-fruity note is desirable along with a floral complex. Jasmin, Tuberose, Gardenia, and many other floral bases, spicy fragrances, etc., can achieve new and interesting ‘lifts’ from this material.
Key Uses in Perfumery
- Fine fragrances and designer perfumes
- Cosmetic fragrances
- Personal care products (soaps, shampoos, lotions)
- Household products and cleaning supplies
Fragrance Blending
Apple ketal fructone serves as an excellent modifier and accent note, particularly effective in:
- Floral compositions (jasmine, tuberose, gardenia)
- Fruity accords
- Wine-like and fermented fruit notes
- Top-note modifications in complex fragrances
Food and Beverage Uses
Flavor Applications
Apple ketal fructone functions as both a flavour and fragrance agent, possessing a fruity type odor and fruity type flavor.
Specific Food Applications
Fruit-flavored beverages: Enhancing apple, strawberry, and tropical fruit profiles
- Confectionery: Adding depth to fruit-flavored candies and gums.
- Baked goods: Contributing to fruity cake and pastry flavors.
- Dairy products: Flavoring fruit yogurts and milk drinks.
- Alcoholic beverages: Creating wine-like and fermented fruit notes.
Cosmetics and Personal Care Uses
Cosmetic Applications
Apple ketal fructone is extensively used in cosmetics and personal care products, including soap, shampoo, lotion, and perfume.
Product Categories:
- Skincare products (lotions, creams, serums).
- Hair care products (shampoos, conditioners).
- Bath and body products.
- Makeup and color cosmetics.
- Men’s grooming products.
Usage Guidelines
Concentration Levels
- Fragrances: Typically used at 0.1-5% concentration.
- Food Flavoring: Much lower concentrations (ppm levels).
- Cosmetics: Variable depending on product type and application.
Apple ketal fructone stands as a cornerstone ingredient in modern fragrance and flavor formulation. Its unique ability to provide authentic fruity notes with excellent stability and versatility makes it indispensable across multiple industries. From fine perfumery to food flavoring, from cosmetics to household products, fructone continues to enable formulators to create compelling sensory experiences.
Fructone Benefits
Superior Longevity and Tenacity
One of the primary benefits of apple ketal fructone is its exceptional longevity compared to other fruity compounds. more tenacious than many of the fruity acetates, which means fragrances containing this ingredient maintain their scent profile for extended periods. This makes it particularly valuable for creating long-lasting perfumes and personal care products.
Complex Scent Profile
Apple ketal fructone offers a fruity, apple-like smell with pineapple, strawberry, and woody aspects. This complexity allows perfumers to create more nuanced and interesting fragrance compositions.
Versatile Applications in Perfumery
The compound serves multiple functions in fragrance creation:
- Top Note Modifier: Green Floral-types, Wine-like notes, Jasmin, Tuberose, Gardenia, Add-lift, Strawberry, Berry.
- Floral Enhancement: Many floral bases can achieve new and interesting ‘lifts’ from apple ketal fructone.
- Fruity Note Creation: Fructone is used in fruity notes for all types of fruit.
Wide Range of Personal Care Applications
Apple ketal fructone demonstrates excellent performance across numerous product categories. This versatility makes it an ideal ingredient for manufacturers looking to create consistent fragrance experiences across their entire product line.
Cost-Effective Fragrance Solution
Compounding floral and fruity essences in Cosmetics and personal care products. The synthetic nature of apple ketal fructone makes it a more cost-effective alternative to natural fruit extracts while providing consistent quality and availability.
Stability and Reliability
Unlike natural fruit extracts that can vary in quality and availability, synthetic Apple Ketal provides:
- Consistent scent profile
- Reliable supply chain
- Stable pricing
- Predictable performance characteristics
Whether used as a top note modifier in luxury perfumes or as a fruity accent in everyday personal care products, apple ketal fructone continues to demonstrate its value as a cornerstone ingredient in the fragrance industry. Its consistent quality, reliable availability, and excellent performance characteristics ensure it will remain an important component in fragrance formulations for years to come.
Fructone Used in Flavour and Fragrance
A Pomegranate Flavor
Include the following ingredients (by weight, %):
Trans-2-hexenal, 8.2; hexanal, 3.6; cis-3-hexenal, 2.0; ethyl acetate, 0.04; cis-3-hexenol, 1.6; hexanol, 0.72; (trans, trans)-2, 4-hexadienal, 1.8; furanone, 0.28; ethyl acetoacetate, 0.04; antioxidant BHT, 0.08; methyl heptenone, 0.08; benzaldehyde, 0.01; 2-ethylheptanol, 0.04; hexanoic acid, 0.03; fructone, 0.04; phenylethyl alcohol, 0.02; propylene glycol, 81.38; 2-butanone, 0.04.
In conclusion, apple ketal fructone represents a significant advancement in synthetic fragrance technology, offering perfumers and product developers a reliable, versatile, and cost-effective solution for creating complex fruity fragrances. As a bulk fructone manufacturer and supplier in China, we sell different grades of fructone at wholesale prices to large manufacturers and small customers worldwide.